| 1 |
End-tidal CO2 > 55 mm Hg, PaCO2 > 60 mm Hg |
Respiratory acidosis (15) |
Yes |
| 2 |
Unexplained sinus tachycardia, ventricular tachycardia, or ventricular fibrillation |
Cardiac involvement (3) |
Yes |
| 3 |
Base deficit > 8 mEq/L, pH < 7.25 |
Metabolic acidosis (10) |
Yes |
| 4 |
Generalized rigidity, severe masseter muscle rigidity |
Muscle rigidity (15) |
Yes |
| 5 |
Serum creatine kinase concentration > 20,000/L units, cola-colored urine, excess myoglobin in
urine or serum, plasma [K+] > 6 mEq/L |
Muscle breakdown (15) |
Yes |
| 6 |
Rapidly increasing temperature, T > 38.8° C |
Temperature increase (15) |
Yes |
| 7 |
Rapid reversal of MH signs with dantrolene (score=5) |
Other |
Yes |
|
Elevated resting serum creatine kinase concentration (score=10) |
Other |
Yes |
| 8 |
Consistent with autosomal dominant inheritance |
Family history (15) |
No |
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